determining the effect of estradiol, oxytocin, prostaglandin e1 and relaxin on cervix dilation and pregnancy rate of zandi breed sheep

the aim of this study was to evaluate the effect of estradiol (e2), oxytocin (ot), relaxin (relaximol) injection and prostaglandin e1 (misoprostol) suppository on the cervix dilation, time of cervical dilation persistency and pregnancy rate of zandi ewes using artificial insemination. eighty 3-4 years old and 55±2.5 kg weight ewes were used for this study. in experiment 1, the ewes were assigned to four equally groups. the groups were received 100 µl e2, 100 iu of ot, 5 ml relaximol and 200 µg misoprostol, respectively. then, cervical dilation and time of cervical dilation persistency were examined at four times. e2 had no effect on cervical dilation and time of cervical dilation persistency (p>0.05). using of ot, relaximol and misoprostol lead to cervical dilation (p